Which of the following is a sign of severe electrolyte imbalance?

Weakness and fatigue are significant indicators of severe electrolyte imbalance due to the essential role that electrolytes play in various physiological functions, including nerve conduction, muscle contraction, and hydration. An imbalance, whether it be from low levels of critical electrolytes like potassium, sodium, or calcium, can disrupt these processes, leading to muscle weakness, cramping, or extreme fatigue. This is particularly evident in conditions like hyponatremia (low sodium levels) or hypokalemia (low potassium levels), where muscle strength and overall energy are compromised.

Other options, while they may relate to health issues, are not as directly linked to severe electrolyte imbalances. Increased appetite can be influenced by numerous factors, not specifically tied to electrolytes. Dry skin might suggest dehydration or nutritional deficiencies but does not specifically indicate a critical imbalance of electrolytes. Rapid weight gain could result from fluid retention, which might occur due to various reasons, including hormonal changes or other health conditions, but it is not a direct sign of an electrolyte crisis.